Clinical studies
Altogether, eleven clinical research protocols at standard fields (1.5 T and 3 T) and low- and very low-fields are planned in V|LF-Spiro3D with 145 healthy adults and children, 240 adult and 90 child patients to amount to 570 lung function tests, 210 forced oscillation tests, 240 PREFUL, 60 4D flow MRI, 1470 MRI-compatible standard spirometry and 1780 3D MR spirometry datasets. Besides, the subject’s experience will be probed on 80 subjects in a thirteenth protocol through 160 surveys and 80 interviews.
Protocols
a-gb-Spiro3D
3D MR spirometry in healthy adults against gravity and reversibility
a-ast-Spiro3D
3D MR Spirometry in adults with severe asthma before and after biotherapy
a-bos-Spiro3D
3D MR spirometry in Lung Transplant Recipients with and without bronchiolitis obliterans syndrome
a-copd-Spiro3D
3D MR spirometry in adults with COPD against reversibility testing
p-ast-Spiro3D
3D MR spirometry in children with asthma
p-bpd-Spiro3D
3D MR spirometry in patients with bronchopulmonary dysplasia
p-cf-Spiro3D
3D MR spirometry in patients with cystic fibrosis
a-glf-Spiro3D
Low-field 3D MR spirometry in healthy adults against gravity
p-glf-Spiro3D
Low-field 3D MR spirometry in healthy children against gravity
a-pidlf-Spiro3D
Functional lung imaging at 0.55 T MRI using 3D MR spirometry and Fourier decomposition
a-gfcivlf-Spiro3D
Field cycling imaging and very-low-field 3D MR spirometry in healthy adults against gravity
